Megaesophagus: achalasia, scleroderma, distal narrowing from tumor or stricture, Chagas
Contrast extravasation: esophagitis, tumor, vomiting (MW tear, Boerhaave), TE fistula, foregut duplication cyst with communication to esophagus, iatrogenic, trauma
Gastroenteric fistula: PUD, Crohn’s, CA, iatrogenic, surgery Free air: surgery and laparoscopy, perforated ulcer, perforated distal bowel (IBD, diverticulitis, tumor)
UGI surgery: plication defect, marginal ulcer, bezoar, chronic gastritis, leak, obstruction, intussusception (jejunogastric), gastric CA, afferent loop syndrome, malabsorption
General GI DDx: Crohn’s, lymphoma, TB (infection), mets, CA, radiation, ischemia Mucosal: acute angle, absence of normal mucosal pattern, irregular fuzzy margin
Submucosal: obtuse angle, presence of normal mucosal pattern, smooth distinct margin